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KMID : 0359319960360020441
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Korean Journal of Veterinary Research
1996 Volume.36 No. 2 p.441 ~ p.445
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Necrotizing meningoencephalitis in a pug dog in Korea
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김재훈/Kim, Jae Hoon
김대용/권오경/박은정/Kim, Dae Yong/Kweon, Oh Kyeong/Bak, Eun Jung
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Abstract
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A case of necrotizing meningoencephalitis was described in a 3-year-old female pug dog.
Significant histopathological changes were confined to the brain.
Histopathologically, brain lesion of the pug dog was characterized by (1) severe lymphocyte, plasma cell and macrophage infiltration in the meninges and gray and white matter of the cerebral hemisphere, (2) perivascular mononuclear cell cuffing and (3) focal polioencephalomalacia in the gray matter of cerebrum.
Replicate sections of the brain and lung were negative for fungal infection, canine distemper and toxoplasmosis on PAS stain and immunohistochemistry, respectively.
Based on clinical signs, histopathological and immunohistochemical studies, this case was diagnosed as necrotizing meningoencephalitis in pug dog that had not been preriously described in Korea.
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